Estrogen patch shortage continues as women scramble after FDA removed black box warning

NEW YORK - Women across the United States are still struggling to fill estrogen patch prescriptions, according to a New York Post report on the ongoing shortage.

In November 2025, the Food and Drug Administration removed a black box warning from estrogen-based hormone therapy that had stood for more than 20 years. Prescriptions rose. Within months, pharmacies reported empty shelves for several estradiol patch brands. Patients are often limited to a one-month supply, so each refill becomes a search.

Elizabeth Borsting told the Post her Costco pharmacy was out and suggested a pickup 40 miles away. She sent the prescription nearly 400 miles to Utah, where her husband was traveling, to keep therapy going. Amy Roberts of Utah said she has driven about 45 minutes to Salt Lake City several times, spending about $25 in gas each trip, after night sweats and severe brain fog returned without the medicine.

Pharmacist and shortage trackers have said multiple patch formulations remain intermittently unavailable even when the FDA has not always listed them as formally short. Manufacturers say they are running at capacity. Industry voices cited by women's health outlets estimate catch-up could take many more months. Some patients report switching brands, using gels, or calling multiple pharmacies. Clinicians warn against stretching patches longer than labeled without guidance, because skin irritation and uneven dosing can follow.